iPTMnet Report for O43251 (RBFOX2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43251 / RFOX2_HUMAN
Protein Name RNA binding protein fox-1 homolog 2
Gene Name Name: RBFOX2
Synonyms:FOX2,HRNBP2,RBM9,RTA;
Organism Homo sapiens (Human)

PRO ID PR:O43251
DAG View
PRO Name RNA binding protein fox-1 homolog 2 (human)
Definition An RNA binding protein fox-1 homolog 2 that is encoded in the genome of human.
Short Label hRBFOX2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43251 (RBFOX2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus 22028470
H67 Phosphorylation UniProt 24275569
S106 Phosphorylation PhosphoSitePlus
T119 Phosphorylation PhosphoSitePlus
R138 Methylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K214 Sumoylation PhosphoSitePlus
G249 Methylation UniProt 24129315
G267 Methylation UniProt 24129315
F268 Methylation UniProt 24129315
A277 Methylation UniProt 24129315
R281 Methylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
R297 Methylation PhosphoSitePlus
R329 Methylation PhosphoSitePlus   UniProt 24129315
Y380 Phosphorylation PhosphoSitePlus
R381 Methylation PhosphoSitePlus
R386 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T15 Phosphorylation PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
R249 Methylation PhosphoSitePlus
R254 Methylation PhosphoSitePlus
R256 Methylation PhosphoSitePlus
R258 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
R267 Methylation PhosphoSitePlus
R272 Methylation PhosphoSitePlus
R274 Methylation PhosphoSitePlus
R276 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
R20 Methylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
R268 Methylation PhosphoSitePlus
R273 Methylation PhosphoSitePlus
R275 Methylation PhosphoSitePlus
R277 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R258 W258 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]
R276 W276 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]