iPTMnet Report for O43242 (PSMD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43242 / PSMD3_HUMAN
Protein Name 26S proteasome non-ATPase regulatory subunit 3
Gene Name Name: PSMD3
Organism Homo sapiens (Human)

PRO ID PR:O43242
DAG View
PRO Name 26S proteasome non-ATPase regulatory subunit 3 (human)
Definition A 26S proteasome non-ATPase regulatory subunit 3 that is encoded in the genome of human.
Short Label hPSMD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43242 (PSMD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Sumoylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
K14 Acetylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
K38 Sumoylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K54 Acetylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
T104 O-Glycosylation GlyGen 33214551, 35138101, 30397120, ...30379171, 34725712, 34019948, 32870666, 33465208
S105 O-Glycosylation GlyGen 33214551, 35138101, 30397120, ...30379171, 34725712, 34019948, 32870666, 33465208
S105 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
Y302 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
Y392 Phosphorylation PhosphoSitePlus
T393 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
T405 Phosphorylation PhosphoSitePlus
S413 O-Glycosylation GlyGen 33214551, 35138101, 30397120, ...30379171, 34725712, 34019948, 32870666, 33465208
S413 Phosphorylation PhosphoSitePlus
Y414 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus   UniProt 23186163
K425 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus   UniProt 23186163
K440 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
K523 Methylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S418 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T104 I104 Biomuta DOID:4159 / skin cancer [ cosmic ]
K186 Q186 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K209 T209 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K315 N315 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T393 I393 Biomuta DOID:363 / uterine cancer [ icgc ]
Y414 C414 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S481 C481 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S481 F481 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K492 N492 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]