iPTMnet Report for O43196 (MSH5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43196 / MSH5_HUMAN
Protein Name MutS protein homolog 5
Gene Name Name: MSH5
Organism Homo sapiens (Human)

PRO ID PR:O43196
DAG View
PRO Name MutS protein homolog 5 (human)
Definition A MutS protein homolog 5 that is encoded in the genome of human.
Short Label hMSH5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43196 (MSH5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K105 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S237 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
Y549 Phosphorylation PhosphoSitePlus
K584 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
Y742 Phosphorylation PhosphoSitePlus   RLIMS-P 22401567
K766 Ubiquitination PhosphoSitePlus
K772 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S240 L240 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y242 C242 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]