iPTMnet Report for O43189 (PHF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43189 / PHF1_HUMAN
Protein Name PHD finger protein 1
Gene Name Name: PHF1
Synonyms:PCL1;
Organism Homo sapiens (Human)

PRO ID PR:O43189
DAG View
PRO Name PHD finger protein 1 (human)
Definition A PHD finger protein 1 that is encoded in the genome of human.
Short Label hPHF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43189 (PHF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
T343 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
G360 Phosphorylation UniProt 18669648
S420 Phosphorylation PhosphoSitePlus   UniProt 23186163
S488 O-Glycosylation GlyGen 32938750, 29351928
S515 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
R530 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S522 Phosphorylation HPRD 19007248
Site PTM Type PTM Enzyme Score Source PMID
Y156 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
S360 Phosphorylation HPRD   PhosphoSitePlus 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K172 M172 Biomuta DOID:4159 / skin cancer [ cosmic ]
K313 M313 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K313 R313 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]