Protein Information

Cytoscape View


UniProt AC / UniProt ID O43181 / NDUS4_HUMAN
Protein Name NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial precursor
Gene Name Name: NDUFS4
Organism Homo sapiens (Human)

PRO ID PR:O43181
DAG View
PRO Name NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (human)
Definition An NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial that is encoded in the genome of human.
Short Label hNDUFS4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43181 (NDUFS4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T32 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16094384
S34 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16094384
S157 Phosphorylation HPRD 20068231
S165 Phosphorylation HPRD   PhosphoSitePlus 20068231
K168 Acetylation PhosphoSitePlus
S173 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 20433953


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S165 Y165 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S173 A173 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]