iPTMnet Report for O43175 (PHGDH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43175 / SERA_HUMAN
Protein Name D-3-phosphoglycerate dehydrogenase
Gene Name Name: PHGDH
Synonyms:PGDH3;
Organism Homo sapiens (Human)

PRO ID PR:O43175
DAG View
PRO Name D-3-phosphoglycerate dehydrogenase (human)
Definition A D-3-phosphoglycerate dehydrogenase that is encoded in the genome of human.
Short Label hPHGDH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43175 (PHGDH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R7 Methylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 24275569
K21 Sumoylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
K33 Acetylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
C48 Methylation IEDB 31844290
S55 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus 23374352
T57 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus 23374352
K58 Acetylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
R75 Methylation PhosphoSitePlus
T78 Phosphorylation Q05513 (PRKCZ) HPRD   PhosphoSitePlus   UniProt 23186163, 18452278, 23374352, ...24275569, 20166139
T89 Phosphorylation HPRD 20068231
S105 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
S127 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
S166 O-Glycosylation GlyGen 23301498, 16408927, 33214551, ...35138101, 30397120, 30379171, 34725712, 34019948, 35083852, 32119511, 28510447, 33465208
R236 Methylation PhosphoSitePlus
R247 Methylation PhosphoSitePlus
C281 S-Nitrosylation dbSNO 22178444, 19366988, 18335467
K289 Acetylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
T322 O-Glycosylation GlyGen 23301498, 16408927, 33214551, ...35138101, 30397120, 30379171, 34725712, 34019948, 35083852, 32119511, 28510447, 33465208
S323 O-Glycosylation GlyGen 33465208
S326 Phosphorylation HPRD 20068231
K330 Ubiquitination PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
T358 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
C369 S-Nitrosylation dbSNO 19483679, 19101475, 22178444, ...19366988, 18335467
S371 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K380 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
T480 Phosphorylation HPRD   PhosphoSitePlus 20068231
K522 Ubiquitination PhosphoSitePlus