Protein Information

Cytoscape View


UniProt AC / UniProt ID O43173 / SIA8C_HUMAN
Protein Name Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
Gene Name Name: ST8SIA3
Synonyms:SIAT8C;
Organism Homo sapiens (Human)

PRO ID PR:O43173
DAG View
PRO Name sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase (human)
Definition A sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase that is encoded in the genome of human.
Short Label hST8SIA3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43173 (ST8SIA3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T41 Phosphorylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
N93 N-Glycosylation GlyGen   UniProt 26192331
N113 N-Glycosylation GlyGen   UniProt 26192331
S152 Phosphorylation PhosphoSitePlus
N160 N-Glycosylation GlyGen   UniProt 26192331
N206 N-Glycosylation GlyGen   UniProt 26192331
S213 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N113 I113 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]