Protein Information

Cytoscape View

UniProt AC / UniProt ID O43157 / PLXB1_HUMAN
Protein Name Plexin-B1 precursor
Gene Name Name: PLXNB1
Organism Homo sapiens (Human)

PRO ID PR:O43157
DAG View
PRO Name plexin-B1 (human)
Definition A plexin-B1 that is encoded in the genome of human.
Short Label hPLXNB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O43157 (PLXNB1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S674 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus
S691 O-Glycosylation PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
S693 O-Glycosylation GlyGen   PhosphoSitePlus 30459171
S693 Phosphorylation PhosphoSitePlus
T696 O-Glycosylation PhosphoSitePlus
S790 O-Glycosylation GlyGen 30459171
S795 O-Glycosylation GlyGen 30459171
S834 O-Glycosylation GlyGen 30459171
N1183 N-Glycosylation GlyGen 23090970, 29391424
N1253 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977, ...23090970, 29391424, 19349973, 29671580
N1330 N-Glycosylation GlyGen   UniProt 19159218
K1524 Ubiquitination PhosphoSitePlus
S1535 Phosphorylation PhosphoSitePlus
S1612 Phosphorylation PhosphoSitePlus
Y1667 Phosphorylation PhosphoSitePlus
Y1708 Phosphorylation P04626 (ERBB2) PhosphoSitePlus 19805522
T1727 Phosphorylation PhosphoSitePlus
Y1732 Phosphorylation P04626 (ERBB2) PhosphoSitePlus 19805522
K1855 Ubiquitination PhosphoSitePlus
T1870 Phosphorylation PhosphoSitePlus
S1902 Phosphorylation PhosphoSitePlus
T1928 Phosphorylation PhosphoSitePlus
R2051 Methylation PhosphoSitePlus
K2131 Ubiquitination PhosphoSitePlus


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048826 (hPLXNB1/SigPep-/PhosTyr+) p PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S693 P693 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S693 Y693 Biomuta DOID:1324 / lung cancer [ icgc ]
T696 P696 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
N1253 S1253 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
N1253 K1253 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1902 R1902 Biomuta DOID:3571 / liver cancer [ icgc ]
T1928 I1928 Biomuta DOID:1909 / melanoma [ cosmic ]