iPTMnet Report for O43157 (PLXNB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43157 / PLXB1_HUMAN
Protein Name Plexin-B1 precursor
Gene Name Name: PLXNB1
Synonyms:KIAA0407,PLXN5,SEP;
Organism Homo sapiens (Human)

PRO ID PR:O43157
DAG View
PRO Name plexin-B1 (human)
Definition A plexin-B1 that is encoded in the genome of human.
Short Label hPLXNB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43157 (PLXNB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S674 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus
S691 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S691 Phosphorylation PhosphoSitePlus
S693 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S693 Phosphorylation PhosphoSitePlus
T696 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S790 O-Glycosylation GlyGen 30459171, 25813380
S793 O-Glycosylation GlyGen 25813380
S795 O-Glycosylation GlyGen 30459171, 25813380
S834 O-Glycosylation GlyGen 30459171
N1183 N-Glycosylation GlyGen 23090970, 29391424
T1224 O-Glycosylation GlyGen 25813380
N1253 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977, ...23090970, 29391424, 19349973, 29671580
N1330 N-Glycosylation GlyGen   UniProt 19159218
K1524 Ubiquitination PhosphoSitePlus
S1535 Phosphorylation PhosphoSitePlus
S1612 Phosphorylation PhosphoSitePlus
Y1667 Phosphorylation PhosphoSitePlus
Y1708 Phosphorylation P04626 (ERBB2) PhosphoSitePlus 19805522
T1727 Phosphorylation PhosphoSitePlus
Y1732 Phosphorylation P04626 (ERBB2) PhosphoSitePlus 19805522
K1855 Ubiquitination PhosphoSitePlus
T1870 Phosphorylation PhosphoSitePlus
S1902 Phosphorylation PhosphoSitePlus
T1928 Phosphorylation PhosphoSitePlus
R2051 Methylation PhosphoSitePlus
K2131 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N1253 N-Glycosylation PRO 29671580


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048826 (hPLXNB1/SigPep-/PhosTyr+) p PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S693 P693 Biomuta DOID:3565 / meningioma [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S693 Y693 Biomuta DOID:1324 / lung cancer [ icgc ]
T696 P696 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
N1253 S1253 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]
N1253 K1253 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1870 I1870 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1928 I1928 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R2051 M2051 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]