iPTMnet Report for O43156 (TTI1)
Protein Information
UniProt AC / UniProt ID | O43156 / TTI1_HUMAN |
Protein Name | TELO2-interacting protein 1 homolog |
Gene Name | Name: TTI1 Synonyms:KIAA0406,SMG10; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43156 |
PRO Name | TELO2-interacting protein 1 homolog (human) |
Definition | A TELO2-interacting protein 1 homolog that is encoded in the genome of human. |
Short Label | hTTI1 |
Category | organism-gene |
O43156 (TTI1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S167 | Phosphorylation | score1 | PhosphoSitePlus | |||
K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
K261 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y274 | Phosphorylation | score1 | PhosphoSitePlus | |||
T283 | Phosphorylation | score1 | PhosphoSitePlus | |||
C297 | Methylation | score1 | IEDB | 31844290 | ||
K353 | Ubiquitination | score1 | PhosphoSitePlus | |||
K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
S453 | Phosphorylation | score1 | PhosphoSitePlus | |||
S459 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18691976, 23186163, 17081983, ... | ||
K461 | Ubiquitination | score1 | PhosphoSitePlus | |||
C492 | Methylation | score1 | IEDB | 31844290 | ||
K547 | Ubiquitination | score1 | PhosphoSitePlus | |||
C646 | Methylation | score1 | IEDB | 31844290 | ||
Y816 | Phosphorylation | score1 | IEDB | 35494241 | ||
K818 | Ubiquitination | score1 | PhosphoSitePlus | |||
S828 | Phosphorylation | score4 | PhosphoSitePlus Signor UniProt | 23263282, 23186163 | ||
S828 | Phosphorylation | P68400 (CSNK2A1) | score3 | PhosphoSitePlus Signor | 23263282 | |
K877 | Ubiquitination | score1 | PhosphoSitePlus | |||
K939 | Ubiquitination | score1 | PhosphoSitePlus | |||
K955 | Ubiquitination | score1 | PhosphoSitePlus | |||
S959 | Phosphorylation | score0 | HPRD | 20068231 | ||
T962 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S967 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
Y1077 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K253 | N253 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K261 | N261 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S828 | L828 | Biomuta | [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
K877 | Q877 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
S959 | F959 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |