iPTMnet Report for O43150 (ASAP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43150 / ASAP2_HUMAN
Protein Name Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
Gene Name Name: ASAP2
Synonyms:DDEF2,KIAA0400;
Organism Homo sapiens (Human)

PRO ID PR:O43150
DAG View
PRO Name Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (human)
Definition An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 that is encoded in the genome of human.
Short Label hASAP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43150 (ASAP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K81 Ubiquitination PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K242 Acetylation PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
K321 Acetylation PhosphoSitePlus
K325 Acetylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
T556 Phosphorylation PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
Y689 Phosphorylation PhosphoSitePlus
S701 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18088087, 17081983, ...18669648, 23186163, 20068231
S712 Phosphorylation PhosphoSitePlus
S722 Phosphorylation PhosphoSitePlus
Y724 Phosphorylation PhosphoSitePlus
S728 Phosphorylation PhosphoSitePlus
Y763 Phosphorylation PhosphoSitePlus
S800 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S820 Phosphorylation PhosphoSitePlus
S822 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T845 Phosphorylation PhosphoSitePlus
T900 Phosphorylation PhosphoSitePlus
T903 Phosphorylation PhosphoSitePlus   UniProt 21406692
Site PTM Type PTM Enzyme Score Source PMID
S701 Phosphorylation HPRD 17322306, 18088087, 18767875, ...19651622, 18669648, 18707149, 19415658, 20068231
S822 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T798 Phosphorylation PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K242 R242 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S285 F285 Biomuta DOID:4159 / skin cancer [ cosmic ]
S294 N294 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
T336 S336 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T336 I336 Biomuta DOID:263 / kidney cancer [ cosmic ]
S338 Y338 Biomuta DOID:1324 / lung cancer [ cosmic ]
K405 N405 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K546 N546 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T556 M556 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S722 R722 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y763 H763 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T800 M800 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S820 Y820 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S820 F820 Biomuta [ cosmic ]
T845 M845 Biomuta DOID:9256 / colorectal cancer [ cosmic ]