iPTMnet Report for O43147 (SGSM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43147 / SGSM2_HUMAN
Protein Name Small G protein signaling modulator 2
Gene Name Name: SGSM2
Synonyms:KIAA0397,RUTBC1;
Organism Homo sapiens (Human)

PRO ID PR:O43147
DAG View
PRO Name small G protein signaling modulator 2 (human)
Definition A small G protein signaling modulator 2 that is encoded in the genome of human.
Short Label hSGSM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43147 (SGSM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K100 Ubiquitination PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
R412 Methylation PhosphoSitePlus
R419 Methylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
K554 Ubiquitination PhosphoSitePlus
K590 Acetylation PhosphoSitePlus
K611 Acetylation PhosphoSitePlus
K631 Ubiquitination PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S444 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S105 N105 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S402 F402 Biomuta DOID:4159 / skin cancer [ cosmic ]
R412 W412 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
K545 E545 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S637 T637 Biomuta DOID:4606 / bile duct cancer [ cosmic ]