Protein Information

Cytoscape View


UniProt AC / UniProt ID O35099 / M3K5_MOUSE
Protein Name Mitogen-activated protein kinase kinase kinase 5
Gene Name Name: Map3k5
Synonyms:Ask1,Mekk5;
Organism Mus musculus (Mouse)

PRO ID PR:O35099
DAG View
PRO Name mitogen-activated protein kinase kinase kinase 5 (mouse)
Definition A mitogen-activated protein kinase kinase kinase 5 that is encoded in the genome of mouse.
Short Label mMAP3K5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O35099 (Map3k5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S90 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
T843 Phosphorylation PhosphoSitePlus
T845 Phosphorylation O35099 (Map3k5) , Q61846 (Melk) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 22399290, 18948261, 17342315, ...26317424, 11920685, 22530568, 28939911, 17015619, 27063938
T849 Phosphorylation O35099 (Map3k5) phospho.ELM   PhosphoSitePlus   UniProt 11920685
T963 Phosphorylation PhosphoSitePlus
S965 Phosphorylation phospho.ELM   PhosphoSitePlus 17242355
S973 Phosphorylation PhosphoSitePlus   UniProt 16648474
S1036 Phosphorylation PhosphoSitePlus
S1040 Phosphorylation PhosphoSitePlus
T1066 Phosphorylation PhosphoSitePlus
S1079 Phosphorylation PhosphoSitePlus
S1310 Phosphorylation PhosphoSitePlus


O35099 (Map3k5) as PTM Enzyme



Substrate Site Score Source PMID
O35099 (Map3k5) T845 phospho.ELM   PhosphoSitePlus   UniProt 11920685
O35099 (Map3k5) T849 UniProt 11920685


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O35099 (Map3k5) T845 P39429 (Traf2) unknown eFIP 17015619