Protein Information

Cytoscape View


UniProt AC / UniProt ID O15554 / KCNN4_HUMAN
Protein Name Intermediate conductance calcium-activated potassium channel protein 4
Gene Name Name: KCNN4
Synonyms:IK1,IKCA1,KCA4,SK4;
Organism Homo sapiens (Human)

PRO ID PR:O15554
DAG View
PRO Name intermediate conductance calcium-activated potassium channel protein 4 (human)
Definition An intermediate conductance calcium-activated potassium channel protein 4 that is encoded in the genome of human.
Short Label hKCNN4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15554 (KCNN4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S178 Phosphorylation PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
S314 Phosphorylation neXtProt 15243742
T329 Phosphorylation neXtProt   PhosphoSitePlus 15243742
S334 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 25274816, 15243742
H358 Phosphorylation P22392 (NME2) PhosphoSitePlus   Signor   UniProt 17157250, 18796614
S367 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K394 T394 Biomuta DOID:1793 / pancreatic cancer [ icgc, tcga ] DOID:10283 / prostate cancer [ cosmic ]
T398 M398 Biomuta DOID:11934 / head and neck cancer [ tcga ]