iPTMnet Report for O15524 (SOCS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15524 / SOCS1_HUMAN
Protein Name Suppressor of cytokine signaling 1
Gene Name Name: SOCS1
Synonyms:SSI1,TIP3;
Organism Homo sapiens (Human)

PRO ID PR:O15524
DAG View
PRO Name suppressor of cytokine signaling 1 (human)
Definition A suppressor of cytokine signaling 1 that is encoded in the genome of human.
Short Label hSOCS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15524 (SOCS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y80 Phosphorylation PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y80 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y80 H80 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y80 N80 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y80 C80 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y80 S80 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T185 A185 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]