Protein Information

Cytoscape View


UniProt AC / UniProt ID O15519 / CFLAR_HUMAN
Protein Name CASP8 and FADD-like apoptosis regulator precursor
Gene Name Name: CFLAR
Synonyms:CASH,CASP8AP1,CLARP,MRIT;
Organism Homo sapiens (Human)

PRO ID PR:O15519
DAG View
PRO Name CASP8 and FADD-like apoptosis regulator (human)
Definition A CASP8 and FADD-like apoptosis regulator that is encoded in the genome of human.
Short Label hCFLAR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15519 (CFLAR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K49 Ubiquitination PhosphoSitePlus
R122 Methylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus   RLIMS-P 23519470
K167 Ubiquitination PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S193 Phosphorylation P17252 (PRKCA) , P05771 (PRKCB) PhosphoSitePlus   RLIMS-P 19343040
K195 Ubiquitination PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
C254 S-Nitrosylation dbSNO 16246840, 22178444
C259 S-Nitrosylation dbSNO 16246840, 22178444
S273 Phosphorylation P31749 (AKT1) PhosphoSitePlus   Signor 19339247
S314 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S193 Phosphorylation P05771 (PRKCB) , P17252 (PRKCA) PhosphoSitePlus 19343040