iPTMnet Report for O15511 (ARPC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15511 / ARPC5_HUMAN
Protein Name Actin-related protein 2/3 complex subunit 5
Gene Name Name: ARPC5
Synonyms:ARC16;
Organism Homo sapiens (Human)

PRO ID PR:O15511
DAG View
PRO Name actin-related protein 2/3 complex subunit 5 (human)
Definition An actin-related protein 2/3 complex subunit 5 that is encoded in the genome of human.
Short Label hARPC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15511 (ARPC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 O-Glycosylation GlyGen 29485866, 30379171, 28411811, ...28510447, 35254053
K3 Sumoylation PhosphoSitePlus
K3 Ubiquitination PhosphoSitePlus
T5 O-Glycosylation GlyGen 29485866, 30379171, 28411811, ...28510447, 35254053
S7 O-Glycosylation GlyGen 30379171
S8 O-Glycosylation GlyGen 29485866, 30379171, 28411811, ...28510447, 35254053
K13 Ubiquitination PhosphoSitePlus
Y19 Phosphorylation PhosphoSitePlus
K23 Sumoylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
R74 Methylation PhosphoSitePlus
S77 Phosphorylation P49137 (MAPKAPK2) neXtProt   PhosphoSitePlus 12829704
K87 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
T146 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S77 Phosphorylation P49137 (MAPKAPK2) HPRD 12829704, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 L2 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K3 N3 Biomuta DOID:363 / uterine cancer [ icgc ]
K13 N13 Biomuta DOID:1324 / lung cancer [ cosmic ]
K13 M13 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R74 W74 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K100 N100 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K108 R108 Biomuta DOID:10534 / stomach cancer [ cosmic ]