iPTMnet Report for O15492 (RGS16)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15492 / RGS16_HUMAN
Protein Name Regulator of G-protein signaling 16
Gene Name Name: RGS16
Synonyms:RGSR;
Organism Homo sapiens (Human)

PRO ID PR:O15492
DAG View
PRO Name regulator of G-protein signaling 16 (human)
Definition A regulator of G-protein signaling 16 that is encoded in the genome of human.
Short Label hRGS16
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15492 (RGS16) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C12 Methylation IEDB 31844290
K41 Ubiquitination PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
C98 Methylation IEDB 31844290
Y168 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12588871, 11602604
Y168 Phosphorylation P00533 (EGFR) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12588871, 11602604
Y168 Phosphorylation P07948 (LYN) HPRD   PhosphoSitePlus 12588871, 11602604
Y168 Phosphorylation P12931 (SRC) HPRD   phospho.ELM   PhosphoSitePlus   Signor 12588871, 11602604
Y168 Phosphorylation P41240 (CSK) HPRD 12588871, 11602604
K173 Ubiquitination PhosphoSitePlus
Y177 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 12588871, 11602604
Y177 Phosphorylation P00533 (EGFR) HPRD   phospho.ELM   Signor 11602604
Y177 Phosphorylation P07948 (LYN) phospho.ELM   PhosphoSitePlus 12588871
Y177 Phosphorylation P12931 (SRC) phospho.ELM   PhosphoSitePlus   Signor 12588871
S195 Phosphorylation HPRD 11522288


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K41 R41 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S71 I71 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S195 N195 Biomuta DOID:4159 / skin cancer [ cosmic ]
S195 C195 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]