iPTMnet Report for O15457 (MSH4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15457 / MSH4_HUMAN
Protein Name MutS protein homolog 4
Gene Name Name: MSH4
Organism Homo sapiens (Human)

PRO ID PR:O15457
DAG View
PRO Name MutS protein homolog 4 (human)
Definition A MutS protein homolog 4 that is encoded in the genome of human.
Short Label hMSH4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15457 (MSH4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y132 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
T364 Phosphorylation PhosphoSitePlus
T467 Phosphorylation PhosphoSitePlus
Y475 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
T830 O-Glycosylation GlyGen 30379171
T865 Phosphorylation HPRD   phospho.ELM 18669648
S878 Phosphorylation HPRD   phospho.ELM 18669648
T879 Phosphorylation HPRD   phospho.ELM 18669648
Y889 Phosphorylation PhosphoSitePlus
T893 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S348 I348 Biomuta DOID:363 / uterine cancer [ icgc ]
Y475 C475 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S704 L704 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S712 F712 Biomuta DOID:4159 / skin cancer [ cosmic ]
T830 A830 Biomuta DOID:1612 / breast cancer [ icgc ]
T830 N830 Biomuta DOID:1324 / lung cancer [ cosmic ]