iPTMnet Report for O15440 (ABCC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15440 / MRP5_HUMAN
Protein Name ATP-binding cassette sub-family C member 5
Gene Name Name: ABCC5
Synonyms:MRP5;
Organism Homo sapiens (Human)

PRO ID PR:O15440
DAG View
PRO Name ATP-binding cassette sub-family C member 5 (human)
Definition An ATP-binding cassette sub-family C member 5 that is encoded in the genome of human.
Short Label hABCC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15440 (ABCC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K8 Ubiquitination PhosphoSitePlus
Y10 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y17 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus   UniProt 23186163
T41 Phosphorylation IEDB 35494241
S60 Phosphorylation PhosphoSitePlus   UniProt 23186163
S64 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S505 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S509 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T513 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K546 Ubiquitination PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
K798 Acetylation PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus
K805 Acetylation PhosphoSitePlus
K806 Acetylation PhosphoSitePlus
S807 Phosphorylation PhosphoSitePlus
T814 Phosphorylation PhosphoSitePlus
K821 Ubiquitination PhosphoSitePlus
K824 Ubiquitination PhosphoSitePlus
N890 N-Glycosylation GlyGen 24190977
N897 N-Glycosylation GlyGen 24190977
K977 Ubiquitination PhosphoSitePlus
Y1166 Phosphorylation PhosphoSitePlus
Y1202 Phosphorylation PhosphoSitePlus
K1211 Ubiquitination PhosphoSitePlus
K1212 Ubiquitination PhosphoSitePlus
T1216 Phosphorylation PhosphoSitePlus
K1218 Ubiquitination PhosphoSitePlus
K1222 Ubiquitination PhosphoSitePlus
S1268 Phosphorylation PhosphoSitePlus
K1309 Ubiquitination PhosphoSitePlus
Y1423 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S501 Phosphorylation HPRD 20068231
S502 Phosphorylation HPRD 17081983
S504 Phosphorylation HPRD 19651622, 17081983
S505 Phosphorylation HPRD 19651622, 18669648, 20068231
S509 Phosphorylation HPRD 19651622, 18669648, 20068231
T513 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y10 H10 Biomuta DOID:4159 / skin cancer [ cosmic ]
S19 T19 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S64 P64 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S67 Y67 Biomuta DOID:363 / uterine cancer [ icgc ]
S67 F67 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K89 R89 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K383 N383 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S501 Y501 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S504 F504 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S505 N505 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S553 G553 Biomuta DOID:363 / uterine cancer [ icgc ]
S807 L807 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
Y1166 C1166 Biomuta DOID:184 / bone cancer [ cosmic ]
K1211 N1211 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1216 M1216 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]