iPTMnet Report for O15438 (ABCC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15438 / MRP3_HUMAN
Protein Name ATP-binding cassette sub-family C member 3
Gene Name Name: ABCC3
Synonyms:CMOAT2,MLP2,MRP3;
Organism Homo sapiens (Human)

PRO ID PR:O15438
DAG View
PRO Name ATP-binding cassette sub-family C member 3 (human)
Definition An ATP-binding cassette sub-family C member 3 that is encoded in the genome of human.
Short Label hABCC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15438 (ABCC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K160 Ubiquitination PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K265 Methylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
Y720 Phosphorylation PhosphoSitePlus
S767 Phosphorylation IEDB   PhosphoSitePlus 35494241
K803 Ubiquitination PhosphoSitePlus
T882 Phosphorylation PhosphoSitePlus
S884 Phosphorylation PhosphoSitePlus
T887 Phosphorylation PhosphoSitePlus
T896 Phosphorylation PhosphoSitePlus
S908 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
S911 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S912 Phosphorylation PhosphoSitePlus
K931 Ubiquitination PhosphoSitePlus
K938 Ubiquitination PhosphoSitePlus
K1052 Ubiquitination PhosphoSitePlus
S1141 Phosphorylation PhosphoSitePlus
K1177 Ubiquitination PhosphoSitePlus
S1248 Phosphorylation PhosphoSitePlus
K1344 Ubiquitination PhosphoSitePlus
K1498 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S486 Phosphorylation HPRD 20068231
S908 Phosphorylation HPRD 19651622, 18669648
S911 Phosphorylation HPRD 19651622, 18669648
S1248 Phosphorylation HPRD 20068231
T1470 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y231 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K238 N238 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K271 R271 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K278 E278 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K512 N512 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K684 N684 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K803 N803 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K1344 N1344 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1344 E1344 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1470 S1470 Biomuta DOID:9256 / colorectal cancer [ cosmic ]