iPTMnet Report for O15394 (NCAM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15394 / NCAM2_HUMAN
Protein Name Neural cell adhesion molecule 2 precursor
Gene Name Name: NCAM2
Synonyms:NCAM21;
Organism Homo sapiens (Human)

PRO ID PR:O15394
DAG View
PRO Name neural cell adhesion molecule 2 (human)
Definition A neural cell adhesion molecule 2 that is encoded in the genome of human.
Short Label hNCAM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15394 (NCAM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y91 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
N177 N-Glycosylation GlyGen 23090970, 24190977
N219 N-Glycosylation GlyGen 23090970, 24190977
N445 N-Glycosylation GlyGen   UniProt 23090970, 12754519, 29391424, ...24190977
N448 N-Glycosylation GlyGen 24190977
T451 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
N468 N-Glycosylation GlyGen 24190977
N474 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N479 N-Glycosylation GlyGen 24190977
N562 N-Glycosylation GlyGen   UniProt 12754519, 29391424, 24190977
K757 Ubiquitination PhosphoSitePlus
Y760 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
K766 Ubiquitination PhosphoSitePlus
T774 Phosphorylation PhosphoSitePlus
S786 Phosphorylation PhosphoSitePlus
T794 Phosphorylation PhosphoSitePlus
K811 Acetylation PhosphoSitePlus
K836 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T116 Phosphorylation HPRD 20058876
S122 Phosphorylation HPRD 20058876
T795 Phosphorylation HPRD 18510355


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N177 S177 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N219 T219 Biomuta DOID:363 / uterine cancer [ icgc ]
N445 H445 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N445 T445 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N448 S448 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T451 N451 Biomuta DOID:4159 / skin cancer [ cosmic ]
S453 G453 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y760 H760 Biomuta DOID:363 / uterine cancer [ icgc ]
S765 * Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K766 N766 Biomuta DOID:3571 / liver cancer [ cosmic ]
S786 T786 Biomuta DOID:1324 / lung cancer [ cosmic ]
T794 A794 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K811 T811 Biomuta DOID:4159 / skin cancer [ cosmic ]