Protein Information

Cytoscape View


UniProt AC / UniProt ID O15393 / TMPS2_HUMAN
Protein Name Transmembrane protease serine 2 precursor
Gene Name Name: TMPRSS2
Synonyms:PRSS10;
Organism Homo sapiens (Human)

PRO ID PR:O15393
DAG View
PRO Name transmembrane protease serine 2 (human)
Definition A transmembrane protease serine 2 that is encoded in the genome of human.
Short Label hTMPRSS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15393 (TMPRSS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y44 Phosphorylation PhosphoSitePlus
Y45 Phosphorylation PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
T58 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T58 M58 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S61 F61 Biomuta DOID:1909 / melanoma [ icgc, tcga ]