iPTMnet Report for O15382 (BCAT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15382 / BCAT2_HUMAN
Protein Name Branched-chain-amino-acid aminotransferase, mitochondrial precursor
Gene Name Name: BCAT2
Synonyms:BCATM;
Organism Homo sapiens (Human)

PRO ID PR:O15382
DAG View
PRO Name branched-chain-amino-acid aminotransferase, mitochondrial (human)
Definition A branched-chain-amino-acid aminotransferase, mitochondrial that is encoded in the genome of human.
Short Label hBCAT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15382 (BCAT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K44 Acetylation PhosphoSitePlus
K44 Methylation PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
C135 S-Nitrosylation dbSNO 25040305
K141 Acetylation PhosphoSitePlus
Y228 Phosphorylation PhosphoSitePlus
K229 Acetylation PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K246 Acetylation PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K321 Acetylation PhosphoSitePlus   UniProt 19608861
K321 Ubiquitination PhosphoSitePlus
C342 S-Nitrosylation dbSNO 19483679
C345 S-Nitrosylation dbSNO 19483679
K353 Acetylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K377 Acetylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T186 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K141 T141 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T186 R186 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
K374 E374 Biomuta DOID:2531 / hematologic cancer [ cosmic ]