iPTMnet Report for O15347 (HMGB3)
Protein Information
| UniProt AC / UniProt ID | O15347 / HMGB3_HUMAN |
| Protein Name | High mobility group protein B3 |
| Gene Name | Name: HMGB3 Synonyms:HMG2A,HMG4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O15347 |
| PRO Name | high mobility group protein B3 (human) |
| Definition | A high mobility group protein B3 that is encoded in the genome of human. |
| Short Label | hHMGB3 |
| Category | organism-gene |
O15347 (HMGB3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K12 | Acetylation | score1 | PhosphoSitePlus | |||
| S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R24 | Methylation | score1 | PhosphoSitePlus | |||
| K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K43 | Acetylation | score1 | PhosphoSitePlus | |||
| K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C45 | Methylation | score1 | IEDB | 31844290 | ||
| K59 | Acetylation | score1 | PhosphoSitePlus | |||
| K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K82 | Acetylation | score1 | PhosphoSitePlus | |||
| S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T114 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K139 | Acetylation | score1 | PhosphoSitePlus | |||
| K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K145 | Acetylation | score1 | PhosphoSitePlus | |||
| K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K152 | Acetylation | score1 | PhosphoSitePlus | |||
| K161 | Acetylation | score1 | PhosphoSitePlus | |||
| K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K165 | Acetylation | score1 | PhosphoSitePlus | |||
| K170 | Acetylation | score1 | PhosphoSitePlus | |||
| K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K179 | Acetylation | score1 | PhosphoSitePlus | |||
| K179 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R24 | K24 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K30 | N30 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K44 | T44 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| Y71 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| K82 | N82 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S119 | P119 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K126 | N126 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| K161 | N161 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K179 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K179 | N179 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K179 | R179 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
DAG View