iPTMnet Report for O15347 (HMGB3)
Protein Information
UniProt AC / UniProt ID | O15347 / HMGB3_HUMAN |
Protein Name | High mobility group protein B3 |
Gene Name | Name: HMGB3 Synonyms:HMG2A,HMG4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15347 |
PRO Name | high mobility group protein B3 (human) |
Definition | A high mobility group protein B3 that is encoded in the genome of human. |
Short Label | hHMGB3 |
Category | organism-gene |
O15347 (HMGB3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K12 | Acetylation | score1 | PhosphoSitePlus | |||
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
R24 | Methylation | score1 | PhosphoSitePlus | |||
K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
K43 | Acetylation | score1 | PhosphoSitePlus | |||
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
C45 | Methylation | score1 | IEDB | 31844290 | ||
K59 | Acetylation | score1 | PhosphoSitePlus | |||
K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y71 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y78 | Phosphorylation | score1 | PhosphoSitePlus | |||
K82 | Acetylation | score1 | PhosphoSitePlus | |||
S98 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
T114 | Phosphorylation | score1 | PhosphoSitePlus | |||
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
K139 | Acetylation | score1 | PhosphoSitePlus | |||
K139 | Ubiquitination | score1 | PhosphoSitePlus | |||
K145 | Acetylation | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K152 | Acetylation | score1 | PhosphoSitePlus | |||
K161 | Acetylation | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
K165 | Acetylation | score1 | PhosphoSitePlus | |||
K170 | Acetylation | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
K179 | Acetylation | score1 | PhosphoSitePlus | |||
K179 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R24 | K24 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K30 | N30 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K44 | T44 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
Y71 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
K82 | N82 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S119 | P119 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K126 | N126 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
K161 | N161 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K179 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K179 | N179 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K179 | R179 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |