iPTMnet Report for O15327 (INPP4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15327 / INP4B_HUMAN
Protein Name Inositol polyphosphate 4-phosphatase type II
Gene Name Name: INPP4B
Organism Homo sapiens (Human)

PRO ID PR:O15327
DAG View
PRO Name inositol polyphosphate 4-phosphatase type II (human)
Definition An inositol polyphosphate 4-phosphatase type II that is encoded in the genome of human.
Short Label hINPP4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15327 (INPP4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T35 Phosphorylation PhosphoSitePlus
T61 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S290 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
K448 Acetylation PhosphoSitePlus
S468 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T198 Phosphorylation HPRD 18452278
Y792 Phosphorylation HPRD 17322306
S794 Phosphorylation HPRD 17322306


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S149 G149 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S270 F270 Biomuta DOID:363 / uterine cancer [ icgc ]
S290 Y290 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S353 G353 Biomuta DOID:1324 / lung cancer [ cosmic ]
K448 N448 Biomuta DOID:1324 / lung cancer [ cosmic ]
S496 I496 Biomuta DOID:3571 / liver cancer [ cosmic ]
S794 L794 Biomuta DOID:4159 / skin cancer [ cosmic ]