iPTMnet Report for O15318 (POLR3G)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15318 / RPC7_HUMAN
Protein Name DNA-directed RNA polymerase III subunit RPC7
Gene Name Name: POLR3G
Organism Homo sapiens (Human)

PRO ID PR:O15318
DAG View
PRO Name DNA-directed RNA polymerase III subunit RPC7 (human)
Definition A DNA-directed RNA polymerase III subunit RPC7 that is encoded in the genome of human.
Short Label hPOLR3G
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15318 (POLR3G) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R7 Methylation PhosphoSitePlus
R9 Methylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
K89 Acetylation PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
K122 Acetylation PhosphoSitePlus
T133 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T136 Phosphorylation PhosphoSitePlus
S157 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 21406692, 17287340, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R9 C9 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
R9 H9 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T67 K67 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T136 I136 Biomuta DOID:363 / uterine cancer [ icgc ]
T136 A136 Biomuta DOID:10534 / stomach cancer [ cosmic ]