iPTMnet Report for O15305 (PMM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15305 / PMM2_HUMAN
Protein Name Phosphomannomutase 2
Gene Name Name: PMM2
Organism Homo sapiens (Human)

PRO ID PR:O15305
DAG View
PRO Name phosphomannomutase 2 (human)
Definition A phosphomannomutase 2 that is encoded in the genome of human.
Short Label hPMM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15305 (PMM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
K26 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K202 Acetylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S47 L47 Biomuta DOID:1324 / lung cancer [ cosmic ]
K51 E51 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K77 E77 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S137 N137 Biomuta DOID:4159 / skin cancer [ cosmic ]