Protein Information

Cytoscape View


UniProt AC / UniProt ID O15294 / OGT1_HUMAN
Protein Name UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Gene Name Name: OGT
Organism Homo sapiens (Human)

PRO ID PR:O15294
DAG View
PRO Name UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (human)
Definition A UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit that is encoded in the genome of human.
Short Label hOGT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15294 (OGT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
S3 Phosphorylation PhosphoSitePlus 23395175
S3 Phosphorylation P49841 (GSK3B) PhosphoSitePlus 23395175
S4 Phosphorylation PhosphoSitePlus 23395175
S4 Phosphorylation P49841 (GSK3B) PhosphoSitePlus 23395175
K16 Ubiquitination PhosphoSitePlus
S20 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 29021254, 23186163, ...21851590
S20 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
K83 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K168 Acetylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
Y384 Phosphorylation PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
S391 O-Glycosylation GlyGen 23301498, 20668475, 19833729, ...27713473, 30397120, 26374642, 21740066, 28657654, 29577901, 20305658, 32119511, 24760753, 28510447, 15327282, 31527085, 17614351
T393 O-Glycosylation GlyGen 23301498, 20668475, 19833729, ...27713473, 30397120, 26374642, 21740066, 28657654, 29577901, 20305658, 32119511, 24760753, 28510447, 15327282, 31527085, 17614351
S399 O-Glycosylation GlyGen 23301498, 20668475, 19833729, ...27713473, 30397120, 26374642, 21740066, 28657654, 29577901, 20305658, 32119511, 24760753, 28510447, 15327282, 31527085, 17614351
S437 O-Glycosylation GlyGen 23301498, 20668475, 19833729, ...27713473, 30397120, 26374642, 21740066, 28657654, 29577901, 20305658, 32119511, 24760753, 28510447, 15327282, 31527085, 17614351
K440 Ubiquitination PhosphoSitePlus
T454 Phosphorylation PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
K499 Ubiquitination PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K547 Ubiquitination PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
K717 Ubiquitination PhosphoSitePlus
K718 Ubiquitination PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K742 Ubiquitination PhosphoSitePlus
K752 Sumoylation PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
K866 Ubiquitination PhosphoSitePlus
K908 Ubiquitination PhosphoSitePlus
K971 Ubiquitination PhosphoSitePlus
Y976 Phosphorylation PhosphoSitePlus
K982 Ubiquitination PhosphoSitePlus
T985 Phosphorylation PhosphoSitePlus
K991 Acetylation PhosphoSitePlus
K991 Ubiquitination PhosphoSitePlus
S1004 Phosphorylation PhosphoSitePlus
K1010 Ubiquitination PhosphoSitePlus
T1043 O-Glycosylation GlyGen 23301498, 20668475, 19833729, ...27713473, 30397120, 26374642, 21740066, 28657654, 29577901, 20305658, 32119511, 24760753, 28510447, 15327282, 31527085, 17614351
S1045 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation HPRD 20068231
S4 Phosphorylation HPRD 20068231
S11 Phosphorylation HPRD 20068231
T15 Phosphorylation HPRD 20068231
S20 Phosphorylation HPRD 18669648, 20068231
T325 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T315 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K100 M100 Biomuta DOID:1324 / lung cancer [ cosmic ]
S399 F399 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T454 K454 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:2994 / germ cell cancer [ cosmic ]
K716 N716 Biomuta DOID:363 / uterine cancer [ tcga ]
S1004 R1004 Biomuta DOID:1324 / lung cancer [ tcga ]