iPTMnet Report for O15287 (FANCG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15287 / FANCG_HUMAN
Protein Name Fanconi anemia group G protein
Gene Name Name: FANCG
Synonyms:XRCC9;
Organism Homo sapiens (Human)

PRO ID PR:O15287
DAG View
PRO Name Fanconi anemia group G protein (human)
Definition A Fanconi anemia group G protein that is encoded in the genome of human.
Short Label hFANCG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15287 (FANCG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15367677, 20450923, 15299017, ...18212739
K28 Ubiquitination PhosphoSitePlus
C75 Methylation IEDB 31844290
K182 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
S383 Phosphorylation P06493 (CDK1) HPRD   neXtProt   PhosphoSitePlus   RLIMS-P 15367677, 9242535
S387 Phosphorylation P06493 (CDK1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 15367677, 9242535
K430 Ubiquitination PhosphoSitePlus
T487 Phosphorylation P06493 (CDK1) neXtProt 9242535
K491 Ubiquitination PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
T557 Phosphorylation PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PRO 15367677, 18212739
S383 Phosphorylation PRO 15367677, 18212739
S387 Phosphorylation PRO 15367677, 18212739


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000025731 (hFANCG/iso:1/Phos:1) pS7,pS383,pS387 PRO 15367677, 18212739


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 F7 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S7 A7 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S7 T7 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S383 F383 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T487 A487 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K504 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K618 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]