iPTMnet Report for O15254 (ACOX3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15254 / ACOX3_HUMAN
Protein Name Peroxisomal acyl-coenzyme A oxidase 3
Gene Name Name: ACOX3
Synonyms:BRCOX,PRCOX;
Organism Homo sapiens (Human)

PRO ID PR:O15254
DAG View
PRO Name peroxisomal acyl-coenzyme A oxidase 3 (human)
Definition A peroxisomal acyl-coenzyme A oxidase 3 that is encoded in the genome of human.
Short Label hACOX3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15254 (ACOX3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
K49 Ubiquitination PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
Y74 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
T281 Phosphorylation PhosphoSitePlus   UniProt 19369195
Y286 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
C523 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 R73 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T281 I281 Biomuta [ cosmic ]
K291 E291 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]