Protein Information

Cytoscape View


UniProt AC / UniProt ID O15247 / CLIC2_HUMAN
Protein Name Chloride intracellular channel protein 2
Gene Name Name: CLIC2
Organism Homo sapiens (Human)

PRO ID PR:O15247
DAG View
PRO Name chloride intracellular channel protein 2 (human)
Definition A chloride intracellular channel protein 2 that is encoded in the genome of human.
Short Label hCLIC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15247 (CLIC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T8 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
C114 Methylation IEDB 31844290
S121 Phosphorylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
C184 Methylation IEDB 31844290
K189 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K233 Acetylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K233 N233 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T238 A238 Biomuta DOID:363 / uterine cancer [ cosmic ]