iPTMnet Report for O15230 (LAMA5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15230 / LAMA5_HUMAN
Protein Name Laminin subunit alpha-5 precursor
Gene Name Name: LAMA5
Synonyms:KIAA0533,KIAA1907;
Organism Homo sapiens (Human)

PRO ID PR:O15230
DAG View
PRO Name laminin subunit alpha-5 (human)
Definition A laminin subunit alpha-5 that is encoded in the genome of human.
Short Label hLAMA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15230 (LAMA5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R4 Methylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
N95 N-Glycosylation GlyGen 23090970, 29741879, 24190977
T97 O-Glycosylation GlyGen 23271734, 34019948, 28657654
K113 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
N243 N-Glycosylation GlyGen 23090970, 24190977
S245 O-Glycosylation GlyGen 23271734, 34019948, 28657654
Y287 Phosphorylation PhosphoSitePlus
Y288 Phosphorylation PhosphoSitePlus
Y289 Phosphorylation PhosphoSitePlus
N327 N-Glycosylation GlyGen 23090970, 24190977
N479 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N921 N-Glycosylation GlyGen 23090970, 24190977
T1130 Phosphorylation PhosphoSitePlus
S1259 O-Glycosylation GlyGen 30459171
N1330 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N1555 N-Glycosylation GlyGen 23090970, 24190977
K1606 Ubiquitination PhosphoSitePlus
S1804 Phosphorylation PhosphoSitePlus
N2019 N-Glycosylation GlyGen 23090970, 29741879, 24190977
T2021 O-Glycosylation GlyGen 23271734, 34019948, 28657654
S2138 O-Glycosylation GlyGen 23271734, 34019948, 28657654
N2196 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N2209 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 24190977, ...19159218, 34089345
S2211 O-Glycosylation GlyGen 23271734, 34019948, 28657654
S2221 Phosphorylation PhosphoSitePlus
T2257 Phosphorylation PhosphoSitePlus
N2303 N-Glycosylation GlyGen   UniProt 23090970, 19159218, 24190977
S2305 Phosphorylation PhosphoSitePlus
N2423 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 24190977, ...19159218, 34089345
T2425 O-Glycosylation GlyGen 23271734, 34019948, 28657654
T2425 Phosphorylation PhosphoSitePlus
T2429 Phosphorylation PhosphoSitePlus
K2481 Acetylation PhosphoSitePlus
N2501 N-Glycosylation GlyGen   UniProt 19159218
N2568 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K2633 Ubiquitination PhosphoSitePlus
N2707 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...34089345
Y2784 Phosphorylation PhosphoSitePlus
Y2794 Phosphorylation PhosphoSitePlus
T2845 O-Glycosylation GlyGen 25813380
S2944 Phosphorylation PhosphoSitePlus
S2955 Phosphorylation PhosphoSitePlus
S2958 Phosphorylation PhosphoSitePlus
S2961 Phosphorylation PhosphoSitePlus
T2962 Phosphorylation PhosphoSitePlus
T2963 Phosphorylation PhosphoSitePlus
Y3049 Phosphorylation PhosphoSitePlus
K3099 Acetylation PhosphoSitePlus
Y3100 Phosphorylation PhosphoSitePlus
N3107 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
N3287 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S3429 Phosphorylation PhosphoSitePlus
S3690 O-Glycosylation GlyGen 25813380
Site PTM Type PTM Enzyme Score Source PMID
S2715 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K113 N113 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S245 Y245 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S245 F245 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N327 H327 Biomuta DOID:1612 / breast cancer [ cosmic ]
K1606 R1606 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1804 L1804 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2138 N2138 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S2211 F2211 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S2221 R2221 Biomuta DOID:363 / uterine cancer [ cosmic ]
T2425 I2425 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2845 I2845 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S2944 C2944 Biomuta DOID:1612 / breast cancer [ cosmic ]
S2944 P2944 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T2962 S2962 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N3107 H3107 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]