iPTMnet Report for O15213 (WDR46)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15213 / WDR46_HUMAN
Protein Name WD repeat-containing protein 46
Gene Name Name: WDR46
Synonyms:BING4,C6orf11;ORFNames:FP221;
Organism Homo sapiens (Human)

PRO ID PR:O15213
DAG View
PRO Name WD repeat-containing protein 46 (human)
Definition A WD repeat-containing protein 46 that is encoded in the genome of human.
Short Label hWDR46
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15213 (WDR46) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
S41 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 19691289, ...16565220, 18669648, 24275569
S124 Phosphorylation HPRD   PhosphoSitePlus 20068231
K145 Ubiquitination PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
R216 Methylation PhosphoSitePlus
C271 Methylation IEDB 31844290
R389 Methylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
C515 Methylation IEDB 31844290
K533 Sumoylation PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
S561 Phosphorylation HPRD   PhosphoSitePlus 19007248, 19691289
S564 Phosphorylation PhosphoSitePlus
T598 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S124 F124 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R216 Q216 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R389 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R389 L389 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K503 N503 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]