iPTMnet Report for O15212 (PFDN6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15212 / PFD6_HUMAN
Protein Name Prefoldin subunit 6
Gene Name Name: PFDN6
Synonyms:HKE2,PFD6;
Organism Homo sapiens (Human)

PRO ID PR:O15212
DAG View
PRO Name prefoldin subunit 6 (human)
Definition A prefoldin subunit 6 that is encoded in the genome of human.
Short Label hPFDN6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15212 (PFDN6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K8 Ubiquitination PhosphoSitePlus
E12 Methylation IEDB 29786170
K15 Acetylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
K21 Acetylation PhosphoSitePlus   UniProt 19608861
K21 Ubiquitination PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K66 Acetylation PhosphoSitePlus   UniProt 19608861
K66 Sumoylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
T84 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
K128 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
E12 G12 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K21 T21 Biomuta DOID:9256 / colorectal cancer [ cosmic ]