iPTMnet Report for O15164 (TRIM24)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15164 / TIF1A_HUMAN
Protein Name Transcription intermediary factor 1-alpha
Gene Name Name: TRIM24
Synonyms:RNF82,TIF1,TIF1A;
Organism Homo sapiens (Human)

PRO ID PR:O15164
DAG View
PRO Name transcription intermediary factor 1-alpha (human)
Definition A transcription intermediary factor 1-alpha that is encoded in the genome of human.
Short Label hTRIM24
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15164 (TRIM24) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus   UniProt 20068231
S110 Phosphorylation PhosphoSitePlus   UniProt 20068231
T148 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
R469 Methylation PhosphoSitePlus
R481 Methylation PhosphoSitePlus
T580 O-Glycosylation GlyGen 33214551, 32938750, 34019948, ...30620550, 35132862, 32119511
S590 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus   UniProt 23186163
T657 Phosphorylation PhosphoSitePlus
S660 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S663 Phosphorylation PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
S667 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S685 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S687 Phosphorylation PhosphoSitePlus
S696 Phosphorylation PhosphoSitePlus
K702 Sumoylation PhosphoSitePlus
K711 Sumoylation PhosphoSitePlus
K723 Sumoylation PhosphoSitePlus
Y733 Phosphorylation PhosphoSitePlus
K741 Sumoylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S748 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
S768 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 18669648, 20068231, ...24820418
S771 Phosphorylation PhosphoSitePlus
T772 Phosphorylation PhosphoSitePlus
S773 Phosphorylation phospho.ELM 18669648
T776 Phosphorylation PhosphoSitePlus
T786 Phosphorylation PhosphoSitePlus
S797 Phosphorylation PhosphoSitePlus
K801 Sumoylation PhosphoSitePlus
S808 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S811 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
T818 Phosphorylation PhosphoSitePlus   UniProt 21406692
S874 Phosphorylation PhosphoSitePlus
Y916 Phosphorylation PhosphoSitePlus
Y936 Phosphorylation PhosphoSitePlus
K940 Sumoylation PhosphoSitePlus
K949 Sumoylation PhosphoSitePlus
K992 Sumoylation PhosphoSitePlus
Y996 Phosphorylation PhosphoSitePlus
K1002 Ubiquitination PhosphoSitePlus
S1019 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
S1025 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...19690332
S1028 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 19690332
S1042 Phosphorylation PhosphoSitePlus   UniProt 21406692
Site PTM Type PTM Enzyme Score Source PMID
T101 Phosphorylation HPRD 20068231
S110 Phosphorylation HPRD 20068231
S660 Phosphorylation HPRD 19651622, 18669648
S667 Phosphorylation HPRD 18669648
S685 Phosphorylation HPRD 18669648
S687 Phosphorylation HPRD 19664995
S768 Phosphorylation HPRD 17525332, 18669648, 20068231
S771 Phosphorylation HPRD 20068231
T772 Phosphorylation HPRD 20068231
S773 Phosphorylation HPRD 18669648
S808 Phosphorylation HPRD 18669648, 19664995, 20068231
S811 Phosphorylation HPRD 17081983, 19664995, 18452278, ...19651622, 18669648, 20068231
T818 Phosphorylation HPRD 19651622
S1019 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S1025 Phosphorylation HPRD 19413330, 17081983, 18452278, ...19651622, 18669648, 20068231
S1028 Phosphorylation HPRD 19413330, 17322306, 18452278, ...19651622, 18669648, 20068231
S1042 Phosphorylation HPRD 18212344, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T101 Phosphorylation HPRD 20068231
S110 Phosphorylation HPRD 20068231
S626 Phosphorylation HPRD 19651622, 18669648
S633 Phosphorylation HPRD 18669648
S651 Phosphorylation HPRD 18669648
S653 Phosphorylation HPRD 19664995
S734 Phosphorylation HPRD 17525332, 18669648, 20068231
S737 Phosphorylation HPRD 20068231
T738 Phosphorylation HPRD 20068231
S739 Phosphorylation HPRD 18669648
S774 Phosphorylation HPRD 18669648, 19664995, 20068231
S777 Phosphorylation HPRD 17081983, 19664995, 18452278, ...19651622, 18669648, 20068231
T784 Phosphorylation HPRD 19651622
S985 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S991 Phosphorylation HPRD 19413330, 17081983, 18452278, ...19651622, 18669648, 20068231
S994 Phosphorylation HPRD 19413330, 17322306, 18452278, ...19651622, 18669648, 20068231
S1008 Phosphorylation HPRD 18212344, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S110 L110 Biomuta DOID:3571 / liver cancer [ cosmic ]
S153 C153 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S153 N153 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R469 Q469 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R469 W469 Biomuta DOID:363 / uterine cancer [ icgc ]
T580 S580 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S633 F633 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K641 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T657 M657 Biomuta DOID:11615 / penile cancer [ cosmic ]
S663 L663 Biomuta DOID:4159 / skin cancer [ cosmic ]
S667 F667 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S696 N696 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S737 C737 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S737 F737 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T738 A738 Biomuta DOID:363 / uterine cancer [ cosmic ]
S748 F748 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S762 F762 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S771 C771 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S771 F771 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T772 A772 Biomuta DOID:363 / uterine cancer [ cosmic ]
S774 F774 Biomuta DOID:4159 / skin cancer [ cosmic ]
S797 F797 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S808 F808 Biomuta DOID:4159 / skin cancer [ cosmic ]
S874 C874 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K1002 N1002 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]