iPTMnet Report for O15121 (DEGS1)
Protein Information
| UniProt AC / UniProt ID | O15121 / DEGS1_HUMAN |
| Protein Name | Sphingolipid delta(4)-desaturase DES1 |
| Gene Name | Name: DEGS1 Synonyms:DES1,MLD;ORFNames:MIG15; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O15121 |
| PRO Name | sphingolipid Delta(4)-desaturase DES1 (human) |
| Definition | A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of human. |
| Short Label | hDEGS1 |
| Category | organism-gene |
DAG ViewO15121 (DEGS1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score3 | UniProt | 19647031, 25255805 | ||
| Y14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K29 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C79 | Methylation | score1 | IEDB | 31844290 | ||
| K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K278 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S307 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18669648 | ||
| K317 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K29 | N29 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K29 | R29 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
