Protein Information

Cytoscape View


UniProt AC / UniProt ID O15091 / MRPP3_HUMAN
Protein Name Mitochondrial ribonuclease P catalytic subunit precursor
Gene Name Name: PRORP
Synonyms:KIAA0391,MRPP3;
Organism Homo sapiens (Human)

PRO ID PR:O15091
DAG View
PRO Name mitochondrial ribonuclease P catalytic subunit (human)
Definition A mitochondrial ribonuclease P catalytic subunit that is encoded in the genome of human.
Short Label hPRORP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15091 (PRORP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K91 Ubiquitination PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y175 Phosphorylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
Y205 Phosphorylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
Y307 Phosphorylation PhosphoSitePlus
Y365 Phosphorylation PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K512 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y205 * Biomuta DOID:1324 / lung cancer [ tcga ]
S214 N214 Biomuta DOID:3571 / liver cancer [ tcga ]
Y307 H307 Biomuta DOID:363 / uterine cancer [ tcga ]
Y365 N365 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]