iPTMnet Report for O15068 (MCF2L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15068 / MCF2L_HUMAN
Protein Name Guanine nucleotide exchange factor DBS
Gene Name Name: MCF2L
Synonyms:KIAA0362,OST;
Organism Homo sapiens (Human)

PRO ID PR:O15068
DAG View
PRO Name guanine nucleotide exchange factor DBS (human)
Definition A guanine nucleotide exchange factor DBS that is encoded in the genome of human.
Short Label hMCF2L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15068 (MCF2L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T96 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
Y222 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
S582 Phosphorylation PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
K608 Acetylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
S620 Phosphorylation PhosphoSitePlus
Y784 Phosphorylation PhosphoSitePlus
S785 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
T902 Phosphorylation PhosphoSitePlus
S965 Phosphorylation PhosphoSitePlus
T972 Phosphorylation PhosphoSitePlus
S975 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T992 Phosphorylation PhosphoSitePlus
Y1000 Phosphorylation PhosphoSitePlus
T1007 Phosphorylation PhosphoSitePlus
S1033 Phosphorylation PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T24 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S371 F371 Biomuta DOID:4159 / skin cancer [ cosmic ]
T902 M902 Biomuta [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ]
Y1000 C1000 Biomuta DOID:363 / uterine cancer [ icgc ]
T1007 A1007 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1033 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]