iPTMnet Report for O15056 (SYNJ2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15056 / SYNJ2_HUMAN
Protein Name Synaptojanin-2
Gene Name Name: SYNJ2
Synonyms:KIAA0348;
Organism Homo sapiens (Human)

PRO ID PR:O15056
DAG View
PRO Name synaptojanin-2 (human)
Definition A synaptojanin-2 that is encoded in the genome of human.
Short Label hSYNJ2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15056 (SYNJ2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
Y130 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S268 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
Y490 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P 23076136
S504 Phosphorylation PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
K543 Ubiquitination PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
S838 Phosphorylation PhosphoSitePlus
T918 Phosphorylation PhosphoSitePlus
S921 Phosphorylation PhosphoSitePlus
T991 Phosphorylation PhosphoSitePlus
S994 Phosphorylation PhosphoSitePlus
K1078 Ubiquitination PhosphoSitePlus
S1095 Phosphorylation PhosphoSitePlus
S1097 Phosphorylation PhosphoSitePlus
S1122 Phosphorylation PhosphoSitePlus
S1124 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1136 Phosphorylation PhosphoSitePlus
S1137 Phosphorylation PhosphoSitePlus
T1141 Phosphorylation PhosphoSitePlus
K1169 Ubiquitination PhosphoSitePlus
S1191 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S1196 Phosphorylation PhosphoSitePlus
T1220 Phosphorylation PhosphoSitePlus
S1251 Phosphorylation PhosphoSitePlus
S1318 Phosphorylation PhosphoSitePlus
Y1411 Phosphorylation PhosphoSitePlus
K1432 Ubiquitination PhosphoSitePlus
S1433 Phosphorylation PhosphoSitePlus
S1434 Phosphorylation PhosphoSitePlus
S1439 Phosphorylation PhosphoSitePlus
T1441 Phosphorylation PhosphoSitePlus
S1443 Phosphorylation PhosphoSitePlus
T1496 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y130 Phosphorylation HPRD 18083107
S825 Phosphorylation HPRD 18491316
S1191 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y61 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S618 C618 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
S1095 P1095 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1097 L1097 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S1122 L1122 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T1141 S1141 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1141 M1141 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5158 / pleural cancer [ cosmic ]