Protein Information

Cytoscape View


UniProt AC / UniProt ID O15054 / KDM6B_HUMAN
Protein Name Lysine-specific demethylase 6B
Gene Name Name: KDM6B
Synonyms:JMJD3,KIAA0346;
Organism Homo sapiens (Human)

PRO ID PR:O15054
DAG View
PRO Name lysine-specific demethylase 6B (human)
Definition A lysine-specific demethylase 6B that is encoded in the genome of human.
Short Label hKDM6B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15054 (KDM6B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S48 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus   UniProt 23186163
T380 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
S627 Phosphorylation PhosphoSitePlus
T637 Phosphorylation PhosphoSitePlus
K689 Acetylation PhosphoSitePlus
K700 Acetylation PhosphoSitePlus
T894 Phosphorylation PhosphoSitePlus
S1025 Phosphorylation PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus
S1042 Phosphorylation PhosphoSitePlus
S1085 Phosphorylation PhosphoSitePlus
K1091 Ubiquitination PhosphoSitePlus
K1109 Sumoylation PhosphoSitePlus
K1115 Ubiquitination PhosphoSitePlus
K1154 Ubiquitination PhosphoSitePlus
S1221 Phosphorylation PhosphoSitePlus
K1338 Ubiquitination PhosphoSitePlus
K1341 Ubiquitination PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus
T1524 Phosphorylation PhosphoSitePlus
S1528 Phosphorylation PhosphoSitePlus
K1534 Ubiquitination PhosphoSitePlus
Y1563 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K487 R487 Biomuta DOID:1324 / lung cancer [ icgc ]
K1341 E1341 Biomuta DOID:4159 / skin cancer [ icgc ]