iPTMnet Report for O15050 (TRANK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15050 / TRNK1_HUMAN
Protein Name TPR and ankyrin repeat-containing protein 1
Gene Name Name: TRANK1
Synonyms:KIAA0342,LBA1;
Organism Homo sapiens (Human)

PRO ID PR:O15050
DAG View
PRO Name TPR and ankyrin repeat-containing protein 1 (human)
Definition A lupus brain antigen 1 that is encoded in the genome of human.
Short Label hTRANK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15050 (TRANK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K312 Methylation PhosphoSitePlus
K561 Ubiquitination PhosphoSitePlus
K565 Acetylation PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
S616 Phosphorylation PhosphoSitePlus
K636 Methylation PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
T669 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
K886 Ubiquitination PhosphoSitePlus
Y918 Phosphorylation PhosphoSitePlus
R1009 Methylation PhosphoSitePlus
K1038 Ubiquitination PhosphoSitePlus
K1179 Acetylation PhosphoSitePlus
K1187 Acetylation PhosphoSitePlus
K1617 Ubiquitination PhosphoSitePlus
K1634 Ubiquitination PhosphoSitePlus
K1641 Ubiquitination PhosphoSitePlus
Y1779 Phosphorylation PhosphoSitePlus
Y1845 Phosphorylation PhosphoSitePlus
T1853 Phosphorylation PhosphoSitePlus
K1858 Ubiquitination PhosphoSitePlus
S1860 Phosphorylation PhosphoSitePlus
Y1861 Phosphorylation PhosphoSitePlus
S1862 Phosphorylation PhosphoSitePlus
K1900 Ubiquitination PhosphoSitePlus
K1926 Ubiquitination PhosphoSitePlus
Y2144 Phosphorylation PhosphoSitePlus
K2246 Methylation PhosphoSitePlus
T2408 Phosphorylation PhosphoSitePlus
K2569 Ubiquitination PhosphoSitePlus
T2664 Phosphorylation PhosphoSitePlus
T2698 Phosphorylation PhosphoSitePlus
S2741 Phosphorylation PhosphoSitePlus
K2855 Acetylation PhosphoSitePlus
Y2900 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S596 A596 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S616 C616 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S662 C662 Biomuta DOID:1324 / lung cancer [ cosmic ]
S704 F704 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1009 Q1009 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1187 T1187 Biomuta DOID:363 / uterine cancer [ icgc ]
K1617 N1617 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1860 F1860 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y1861 C1861 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T2698 S2698 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]