iPTMnet Report for O15049 (N4BP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15049 / N4BP3_HUMAN
Protein Name NEDD4-binding protein 3
Gene Name Name: N4BP3
Synonyms:KIAA0341;
Organism Homo sapiens (Human)

PRO ID PR:O15049
DAG View
PRO Name NEDD4-binding protein 3 (human)
Definition A NEDD4-binding protein 3 that is encoded in the genome of human.
Short Label hN4BP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15049 (N4BP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
Y58 Phosphorylation PhosphoSitePlus
Y83 Phosphorylation PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus
Y87 Phosphorylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S176 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S221 Phosphorylation PhosphoSitePlus
C266 Methylation IEDB 31844290
S279 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
Y503 Phosphorylation PhosphoSitePlus
Y511 Phosphorylation PhosphoSitePlus
Y515 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 F25 Biomuta [ cosmic ]
Y87 H87 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S145 N145 Biomuta DOID:10534 / stomach cancer [ cosmic ]
C266 Y266 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T283 M283 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S459 N459 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y503 C503 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y515 C515 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]