iPTMnet Report for O15034 (RIMBP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15034 / RIMB2_HUMAN
Protein Name RIMS-binding protein 2
Gene Name Name: RIMBP2
Synonyms:KIAA0318,RBP2;
Organism Homo sapiens (Human)

PRO ID PR:O15034
DAG View
PRO Name RIMS-binding protein 2 (human)
Definition A RIMS-binding protein 2 that is encoded in the genome of human.
Short Label hRIMBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15034 (RIMBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S376 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
S628 Phosphorylation PhosphoSitePlus
S665 O-Glycosylation GlyGen 28657654
T666 O-Glycosylation GlyGen 28657654
T667 O-Glycosylation GlyGen 28657654
S690 Phosphorylation PhosphoSitePlus
S696 Phosphorylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
Y710 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
K727 Ubiquitination PhosphoSitePlus
K733 Ubiquitination PhosphoSitePlus
T745 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
S748 Phosphorylation PhosphoSitePlus
S794 Phosphorylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S377 T377 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S377 L377 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S628 R628 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T667 I667 Biomuta DOID:4159 / skin cancer [ cosmic ]
S690 G690 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S721 L721 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S747 I747 Biomuta DOID:1324 / lung cancer [ cosmic ]
S747 N747 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S747 C747 Biomuta DOID:1324 / lung cancer [ cosmic ]
S747 R747 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S832 F832 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]