iPTMnet Report for O15031 (PLXNB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15031 / PLXB2_HUMAN
Protein Name Plexin-B2 precursor
Gene Name Name: PLXNB2
Synonyms:KIAA0315;
Organism Homo sapiens (Human)

PRO ID PR:O15031
DAG View
PRO Name plexin-B2 (human)
Definition A plexin-B2 that is encoded in the genome of human.
Short Label hPLXNB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15031 (PLXNB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K76 Ubiquitination PhosphoSitePlus
C120 Methylation IEDB 31844290
S126 Phosphorylation PhosphoSitePlus
N127 N-Glycosylation GlyGen   UniProt 19159218, 24190977, 23090970, ...29391424, 19349973, 29741879
Y200 Phosphorylation PhosphoSitePlus
N328 N-Glycosylation GlyGen 29391424, 24190977
K343 Ubiquitination PhosphoSitePlus
N391 N-Glycosylation GlyGen 24190977
N401 N-Glycosylation GlyGen 24190977
N402 N-Glycosylation GlyGen 24190977
Y419 Phosphorylation PhosphoSitePlus
S452 Phosphorylation HPRD   PhosphoSitePlus 20068231
C501 Methylation IEDB 33981976
N528 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
S650 Phosphorylation PhosphoSitePlus
K696 Ubiquitination PhosphoSitePlus
S718 O-Glycosylation GlyGen 34019948, 22661428, 35289036, ...33465208
N733 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...29391424, 24190977
K747 Ubiquitination PhosphoSitePlus
N759 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
N795 N-Glycosylation GlyGen 29391424, 24190977
N844 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S846 O-Glycosylation GlyGen 34019948, 22661428, 35289036, ...33465208
K941 Acetylation PhosphoSitePlus
N1002 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
N1049 N-Glycosylation GlyGen 23090970, 29741879, 29391424, ...24190977
N1068 N-Glycosylation GlyGen 29741879
N1099 N-Glycosylation GlyGen 29741879, 24190977
K1105 Ubiquitination PhosphoSitePlus
K1121 Ubiquitination PhosphoSitePlus
T1124 Phosphorylation HPRD   PhosphoSitePlus 20068231
T1138 O-Glycosylation GlyGen 25813380
T1143 O-Glycosylation GlyGen 22661428
S1224 Phosphorylation PhosphoSitePlus
Y1231 Phosphorylation PhosphoSitePlus
K1235 Ubiquitination PhosphoSitePlus
S1244 Phosphorylation PhosphoSitePlus
K1250 Ubiquitination PhosphoSitePlus
R1283 Methylation PhosphoSitePlus
K1290 Ubiquitination PhosphoSitePlus
Y1317 Phosphorylation PhosphoSitePlus
S1320 Phosphorylation PhosphoSitePlus
S1325 Phosphorylation PhosphoSitePlus
S1327 Phosphorylation PhosphoSitePlus
Y1349 Phosphorylation PhosphoSitePlus
Y1410 Phosphorylation PhosphoSitePlus
Y1412 Phosphorylation PhosphoSitePlus
Y1422 Phosphorylation PhosphoSitePlus
K1423 Ubiquitination PhosphoSitePlus
K1442 Ubiquitination PhosphoSitePlus
T1486 O-Glycosylation GlyGen 34019948, 22661428, 35289036, ...33465208
K1491 Ubiquitination PhosphoSitePlus
K1493 Ubiquitination PhosphoSitePlus
Y1499 Phosphorylation PhosphoSitePlus
Y1548 Phosphorylation PhosphoSitePlus
K1560 Ubiquitination PhosphoSitePlus
S1570 Phosphorylation PhosphoSitePlus
R1578 Methylation PhosphoSitePlus
K1602 Ubiquitination PhosphoSitePlus
T1614 Phosphorylation PhosphoSitePlus
Y1621 Phosphorylation PhosphoSitePlus
T1623 Phosphorylation PhosphoSitePlus
S1627 Phosphorylation PhosphoSitePlus
K1667 Ubiquitination PhosphoSitePlus
K1738 Ubiquitination PhosphoSitePlus
K1743 Ubiquitination PhosphoSitePlus
K1750 Ubiquitination PhosphoSitePlus
Y1756 Phosphorylation PhosphoSitePlus
K1817 Ubiquitination PhosphoSitePlus
K1834 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N1002 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S452 I452 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S650 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S650 L650 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
N759 D759 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
N1049 I1049 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K1121 N1121 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1121 M1121 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
T1124 M1124 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T1143 M1143 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1224 N1224 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1231 H1231 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K1250 E1250 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1320 F1320 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S1327 F1327 Biomuta DOID:1319 / brain cancer [ icgc ]
Y1422 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1570 N1570 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1578 C1578 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1614 M1614 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1614 K1614 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1623 R1623 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]