iPTMnet Report for O15020 (SPTBN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15020 / SPTN2_HUMAN
Protein Name Spectrin beta chain, non-erythrocytic 2
Gene Name Name: SPTBN2
Synonyms:KIAA0302,SCA5;
Organism Homo sapiens (Human)

PRO ID PR:O15020
DAG View
PRO Name spectrin beta chain, non-erythrocytic 2 (human)
Definition A spectrin beta chain, non-erythrocytic 2 that is encoded in the genome of human.
Short Label hSPTBN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15020 (SPTBN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 20068231
Y19 Phosphorylation PhosphoSitePlus
S31 Phosphorylation PhosphoSitePlus   UniProt 24275569
K65 Ubiquitination PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
K217 Acetylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
Y277 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
Y477 Phosphorylation PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
Y834 Phosphorylation PhosphoSitePlus
S959 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1060 Phosphorylation PhosphoSitePlus
S1073 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1255 Phosphorylation PhosphoSitePlus
T1300 Phosphorylation PhosphoSitePlus
S1305 Phosphorylation PhosphoSitePlus
Y1306 Phosphorylation PhosphoSitePlus
K1315 Ubiquitination PhosphoSitePlus
K1437 Ubiquitination PhosphoSitePlus
K1447 Ubiquitination PhosphoSitePlus
K1674 Ubiquitination PhosphoSitePlus
Y1676 Phosphorylation PhosphoSitePlus
Y1726 Phosphorylation PhosphoSitePlus
Y1801 Phosphorylation PhosphoSitePlus
K1820 Ubiquitination PhosphoSitePlus
S1853 Phosphorylation PhosphoSitePlus
K1868 Ubiquitination PhosphoSitePlus
S1940 Phosphorylation PhosphoSitePlus
S1964 Phosphorylation PhosphoSitePlus
Y1979 Phosphorylation PhosphoSitePlus
K1987 Ubiquitination PhosphoSitePlus
S2038 Phosphorylation PhosphoSitePlus
S2050 Phosphorylation PhosphoSitePlus
K2053 Ubiquitination PhosphoSitePlus
K2060 Ubiquitination PhosphoSitePlus
K2074 Ubiquitination PhosphoSitePlus
S2171 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
S2192 Phosphorylation PhosphoSitePlus
T2200 Phosphorylation PhosphoSitePlus
K2236 Acetylation PhosphoSitePlus
K2237 Acetylation PhosphoSitePlus
S2254 Phosphorylation PhosphoSitePlus
Y2258 Phosphorylation PhosphoSitePlus
K2262 Ubiquitination PhosphoSitePlus
K2304 Ubiquitination PhosphoSitePlus
T2354 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S2359 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S2384 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 20068231
S1853 Phosphorylation HPRD 20068231
S1940 Phosphorylation HPRD 20068231
S2171 Phosphorylation HPRD 18669648, 20068231, 18452278
S2359 Phosphorylation HPRD 18691976, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 R2 Biomuta DOID:3571 / liver cancer [ cosmic ]
S6 L6 Biomuta DOID:1324 / lung cancer [ cosmic ]
T75 M75 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y82 C82 Biomuta DOID:1324 / lung cancer [ cosmic ]
S99 L99 Biomuta DOID:9256 / colorectal cancer [ cosmic ]