iPTMnet Report for O15018 (PDZD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O15018 / PDZD2_HUMAN
Protein Name PDZ domain-containing protein 2
Gene Name Name: PDZD2
Synonyms:AIPC,KIAA0300,PDZK3;
Organism Homo sapiens (Human)

PRO ID PR:O15018
DAG View
PRO Name PDZ domain-containing protein 2 (human)
Definition A PDZ domain-containing protein 2 that is encoded in the genome of human.
Short Label hPDZD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O15018 (PDZD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T200 Phosphorylation PhosphoSitePlus
T209 Phosphorylation PhosphoSitePlus
R283 Methylation PhosphoSitePlus
R288 Methylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S421 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
Y557 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
S702 Phosphorylation PhosphoSitePlus
S710 Phosphorylation PhosphoSitePlus
T831 Phosphorylation PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
T846 Phosphorylation PhosphoSitePlus
S850 Phosphorylation PhosphoSitePlus
S920 Phosphorylation PhosphoSitePlus
S944 Phosphorylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
S1005 Phosphorylation PhosphoSitePlus
T1024 Phosphorylation PhosphoSitePlus
S1031 Phosphorylation PhosphoSitePlus
T1090 Phosphorylation PhosphoSitePlus
T1093 Phosphorylation PhosphoSitePlus
S1125 Phosphorylation PhosphoSitePlus
T1142 Phosphorylation PhosphoSitePlus
T1146 Phosphorylation PhosphoSitePlus
S1157 Phosphorylation PhosphoSitePlus
T1167 O-Glycosylation GlyGen 30379171, 28657654, 35254053
K1242 Ubiquitination PhosphoSitePlus
S1250 Phosphorylation PhosphoSitePlus
S1270 Phosphorylation PhosphoSitePlus
S1280 Phosphorylation PhosphoSitePlus
S1307 Phosphorylation PhosphoSitePlus
S1309 Phosphorylation PhosphoSitePlus
S1437 Phosphorylation PhosphoSitePlus
S1578 Phosphorylation PhosphoSitePlus
S1592 Phosphorylation PhosphoSitePlus
S1594 Phosphorylation PhosphoSitePlus
S1636 Phosphorylation PhosphoSitePlus
T1637 Phosphorylation PhosphoSitePlus
S1770 Phosphorylation PhosphoSitePlus
K1820 Ubiquitination PhosphoSitePlus
S1829 Phosphorylation PhosphoSitePlus
S1850 Phosphorylation PhosphoSitePlus
S1898 Phosphorylation PhosphoSitePlus
S1919 Phosphorylation PhosphoSitePlus
S1953 Phosphorylation PhosphoSitePlus
S1960 Phosphorylation PhosphoSitePlus
T1966 Phosphorylation PhosphoSitePlus
S1967 Phosphorylation PhosphoSitePlus
S2037 Phosphorylation PhosphoSitePlus
S2041 O-Glycosylation GlyGen 30379171, 28657654, 35254053
Y2133 Phosphorylation PhosphoSitePlus
S2142 Phosphorylation PhosphoSitePlus
S2159 Phosphorylation PhosphoSitePlus
S2189 Phosphorylation PhosphoSitePlus
S2224 Phosphorylation PhosphoSitePlus
S2246 Phosphorylation PhosphoSitePlus
T2254 O-Glycosylation GlyGen 30379171, 28657654, 35254053
S2341 Phosphorylation PhosphoSitePlus
S2374 Phosphorylation PhosphoSitePlus
S2376 Phosphorylation PhosphoSitePlus
S2396 Phosphorylation PhosphoSitePlus
T2409 Phosphorylation PhosphoSitePlus
S2417 Phosphorylation PhosphoSitePlus
S2419 Phosphorylation PhosphoSitePlus
T2422 Phosphorylation PhosphoSitePlus
K2436 Acetylation PhosphoSitePlus
S2438 Phosphorylation PhosphoSitePlus
S2440 Phosphorylation PhosphoSitePlus
K2444 Acetylation PhosphoSitePlus
S2445 Phosphorylation PhosphoSitePlus
T2453 Phosphorylation PhosphoSitePlus
T2455 Phosphorylation PhosphoSitePlus
S2460 Phosphorylation PhosphoSitePlus
S2467 Phosphorylation PhosphoSitePlus
T2472 Phosphorylation PhosphoSitePlus
S2475 Phosphorylation PhosphoSitePlus
S2478 Phosphorylation PhosphoSitePlus
S2480 Phosphorylation PhosphoSitePlus
S2489 Phosphorylation PhosphoSitePlus
S2521 Phosphorylation PhosphoSitePlus
S2530 Phosphorylation PhosphoSitePlus
S2544 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T209 A209 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T209 I209 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R288 T288 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S320 L320 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y557 C557 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S840 F840 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S1031 L1031 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1093 I1093 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1146 A1146 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1157 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1157 W1157 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1250 N1250 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1578 F1578 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1592 L1592 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1829 N1829 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1966 A1966 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2159 L2159 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2341 Y2341 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2417 A2417 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S2419 L2419 Biomuta DOID:1612 / breast cancer [ cosmic ]
S2440 L2440 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T2453 I2453 Biomuta [ cosmic ]
T2453 A2453 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T2472 M2472 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S2475 L2475 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S2530 L2530 Biomuta DOID:363 / uterine cancer [ icgc ]