iPTMnet Report for O14994 (SYN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14994 / SYN3_HUMAN
Protein Name Synapsin-3
Gene Name Name: SYN3
Organism Homo sapiens (Human)

PRO ID PR:O14994
DAG View
PRO Name synapsin-3 (human)
Definition A synapsin-3 that is encoded in the genome of human.
Short Label hSYN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14994 (SYN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T32 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S470 Phosphorylation P06493 (CDK1) , P27361 (MAPK3) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 14732590
S473 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
S488 O-Glycosylation GlyGen 35254053
S541 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
K572 Acetylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S457 F457 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S462 P462 Biomuta DOID:363 / uterine cancer [ icgc ]
S462 F462 Biomuta DOID:4159 / skin cancer [ cosmic ]
S541 C541 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]