iPTMnet Report for O14986 (PIP5K1B)
Protein Information
UniProt AC / UniProt ID | O14986 / PI51B_HUMAN |
Protein Name | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta |
Gene Name | Name: PIP5K1B Synonyms:STM7; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O14986 |
PRO Name | phosphatidylinositol 4-phosphate 5-kinase type-1 beta (human) |
Definition | A phosphatidylinositol 4-phosphate 5-kinase type-1 beta that is encoded in the genome of human. |
Short Label | hPIP5K1B |
Category | organism-gene |
O14986 (PIP5K1B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y105 | Phosphorylation | P43405 (SYK) | score3 | neXtProt PhosphoSitePlus | 19553680 | |
K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
T165 | Phosphorylation | score1 | PhosphoSitePlus | |||
K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
K301 | Methylation | score1 | PhosphoSitePlus | |||
K360 | Ubiquitination | score1 | PhosphoSitePlus | |||
S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
S413 | Phosphorylation | P17252 (PRKCA) | score3 | PhosphoSitePlus RLIMS-P Signor | 23909401 | |
S421 | Phosphorylation | score1 | PhosphoSitePlus | |||
S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
S448 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S421 | L421 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |