iPTMnet Report for O14908 (GIPC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O14908 / GIPC1_HUMAN
Protein Name PDZ domain-containing protein GIPC1
Gene Name Name: GIPC1
Synonyms:C19orf3,GIPC,RGS19IP1;
Organism Homo sapiens (Human)

PRO ID PR:O14908
DAG View
PRO Name PDZ domain-containing protein GIPC1 (human)
Definition A PDZ domain-containing protein GIPC1 that is encoded in the genome of human.
Short Label hGIPC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14908 (GIPC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Methylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
R24 Methylation PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus   UniProt 23186163
K80 Ubiquitination PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
R196 Methylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
R203 Methylation PhosphoSitePlus
T206 Phosphorylation PhosphoSitePlus
K210 Sumoylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus   UniProt 23186163
S225 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
R229 Methylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 24275569
T238 Phosphorylation PhosphoSitePlus
R240 Methylation PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus   UniProt 23186163
S247 Phosphorylation PhosphoSitePlus   UniProt 23186163
R248 Methylation PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S68 N68 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K80 T80 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K128 E128 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R196 L196 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K199 N199 Biomuta DOID:1319 / brain cancer [ icgc ]
T206 A206 Biomuta DOID:1324 / lung cancer [ cosmic ]
T238 S238 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S247 F247 Biomuta DOID:4159 / skin cancer [ cosmic ]
R248 Q248 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R248 W248 Biomuta [ cosmic ]
S258 F258 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]